Dako Autostainer Link 48, Features and Benefits

The DAKO Autostainer Link 48

The DAKO Autostainer Link 48 is an easy-to-use device that allows you to stain slides quickly and easily. It comes with a variety of stains.

Dako Autostainer Link 48 is a simple way to stain slides for immunohistochemistry (IHC) and in situ hybridization (ISH). This slide stainer uses a built-in stainer chamber and comes with a wide range of ready-made reagents.


Dako Autostainer Link 48 Overview

Dako Autostainer Link 48 is an automated slide processing system that provides labs with a compact, bench-top, open system for staining IHC slides, paraffin wax-embedded and frozen tissue sections, cytospins, cell smears, and fine needle aspirates using currently available reagents. controlled by protocols in the DakoLink software.

It is a reliable and efficient system that can process up to 1 to 48 microscope slides and each slide can be programmed to receive different reagents. It has come with up to a 1-year warranty.


Features of the Dako Autostainer Link 48

The Dako Autostainer Link 48 instrument is a reliable and compact bench-top immunohistochemistry (IHC) stainer that is characterized by:

  • A streamlined profile and small footprint that minimizes the impact on valuable laboratory space.
  • 48 slides can be processed in less than three hours. This enables the completion of 96 slides using only one Autostainer Link 48 and one PT Link.
  • Equipped with optimized DakoLink software, ensuring optimal staining results.
  • Equipped with FLEX Ready-to-Use Antibodies and Dako Visualization Systems for H&E, Special Stains, IHC, and ISH.
  • The Autostainer Link 48 runs as an open system, allowing for the use of reagents from multiple vendors. It is also available at the best online prices.

Benefits of Using the Dako Autostainer Link 48

The Dako Autostainer Link 48 is an efficient, reliable, and compact staining system that can process up to 48 slides in less than three hours.

It features a streamlined profile and takes up minimal laboratory bench space. Dako grants the user a license to use one biotinylated secondary antibody and allows the programming of staining procedures.

The EnVision FLEX visualization system on Auto stainer Link 48 is ideal for staining breast carcinoma, urothelial carcinoma, and melanoma tissues. Additionally, this system can help laboratories with companion diagnostic testing using the Dako Agilent PD-L1 IHC 22C3 pharmDx kit.

By using the dako autostainer instruments, laboratories can save up to 45 minutes of their run time compared to the dako  autostainer plus link instrument .

The benefits of using a stainer include speed, accuFracy, consistency, and safety. You also avoid having to manually transfer slides between containers, reducing the chance of contamination.

Finally, the stainer eliminates the need to use hazardous chemicals, making it safer for both you and your staff.


How to Use the Dako Autostainer Link 48

Dako Autostainer Link 48
Dako Autostainer Link 48

The Dako Autostainer Link 48 is a high-performance slide staining machine that can process up to 48 slides in less than three hours. It includes FLEX Ready-to-Use reagents, DakoLink software, PT Link, and Autostainer Link 48, and it has positive identification of slides and reagents that minimize errors and provide exceptional ease-of-use. It can be connected to up to three instruments and three PT Links to one computer, and it has been optimized for use with the Dako PT Link and Dako Autostainer 48S Link platform.

Troubleshooting common issues with the Dako Autostainer Link 48 can be achieved by utilizing the RTU system IR/IS633 Dako based on mAb clone A103 for Autostainer Link 48, the Dako FLEX+ kit, and the Dako M3636 (DAK-CDX2).

In order to provide labs with software and connectivity options that will greatly improve workload management and report generation, Staining is carried out on both the Autostainer Link 48 and Ventana Benchmark GX.

In addition, using the Chromogen: Detection: Dako M3636 (DAK-CDX2) with a 30-minute incubation time at 23°C and a dilution of 1:50 can help to provide a pass rate of 100%, 58% optimal of patient cases.


Regulatory Requirements for Use of Automated Staining Systems

Understanding the regulatory requirements for the use of automated staining systems such as the Dako Autostainer Link 48 is critical for proper implementation. This system can be used for Automated immunohistochemical analysis (IHC) and antibody optimization, as well as for testing such as p53 status in cancer cell lines and FOXP3 regulation.

It is important to ensure that optimized reagents and FLEX Ready-to-Use antibodies are used with the pharmDx (Link) kits, and that appropriate EnVision FLEX visualization is employed. Following these protocols will ensure that tests are performed correctly and efficiently.

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Maintenance and Storage Requirements for the Dako Autostainer Link48

The Dako Autostainer link slide stainer requires regular maintenance and storage to ensure it is functioning correctly. Maintenance includes cleaning the robot arm, replacing the plastic and glass parts, calibrating the microscope, and other steps as specified in the manufacturer’s instructions.
Storage requirements include keeping the device dry and free from dust and dirt, keeping it away from direct sunlight and other sources of heat, and ensuring it is stored at a temperature between 10-27°C.


Dako Autostainer Link 48 is the perfect solution that streamlines your laboratory workflow. This innovative staining system automates the entire staining process, allowing you to save time and increase efficiency in your lab.

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